Marcus Stroman, Anthony Rizzo and more react to MLB's Opening Day delay

Gone is Opening Day -- and there could be more Major League Baseball regular-season games lost for the first time in almost three decades after the players rejected the owners' "best and final offer."

The league and the MLBPA failed to come to an agreement on a new collective bargaining agreement by Tuesday's deadline. In a news conference afterward, commissioner Robert Manfred canceled the first two series of the regular season. Opening Day was scheduled for March 31.

This is the ninth work stoppage in MLB history, the first since the 1994-95 strike. According to ESPN Stats and Information, it's the fifth that resulted in canceled games. Currently, 91 matchups are canceled for the upcoming season. The Oakland Athletics, Los Angeles Dodgers, San Francisco Giants, Miami Marlins, Texas Rangers, Detroit Tigers and New York Yankees share the most for a team with seven apiece. The overall schedule will drop from 162 games to a likely 156 games -- or fewer.

Read More: What we know about the MLB lockout

The news of the failure to reach a new CBA caused a flurry of reactions across social media: