| Boston BOS | | LIVE | | Martin Perez vs J.A. Happ | |
| Oakland OAK | | | | Jesus Luzardo vs Zac Gallen | |
| Seattle SEA | | | | Justus Sheffield vs John Means | |
| Philadelphia PHI | | | | Chase Anderson vs Taijuan Walker | |
| San Diego SD | | | | Blake Snell vs Chad Kuhl | |
| Seattle SEA | | | | Nick Margevicius vs Dean Kremer | |
| New York NYY | | | | Jameson Taillon vs Hyun Jin Ryu | |
| Philadelphia PHI | | | | Aaron Nola vs Marcus Stroman | |
| Texas TEX | | | | Kyle Gibson vs Ryan Yarbrough | |
| Miami MIA | | | | Pablo Lopez vs Max Fried | |
| Chicago CHC | | | | Kyle Hendricks vs Brandon Woodruff | |
| Washington WSH | | | | Stephen Strasburg vs Jack Flaherty | |
| Los Angeles LAA | | | | Dylan Bundy vs Danny Duffy | |
| Cleveland CLE | | | | Shane Bieber vs Lucas Giolito | |
| Detroit DET | | | | Matthew Boyd vs Jake Odorizzi | |
| Cincinnati CIN | | | | Luis Castillo vs Kevin Gausman | |
| Colorado COL | | | | Antonio Senzatela vs Trevor Bauer | |
