Gloucester signing Olly Barkley is unlikely to be reunited with his former club Bath tomorrow.
The pressure is on Gloucester boss Dean Ryan to make changes following last weekend's tame Guinness Premiership home defeat against Leicester.
England international Barkley, who moved to Kingsholm from the Recreation Ground earlier this summer, has been recovering from a wrist injury that put his Gloucester debut on ice.
And that introduction to first team action now faces at least another week's delay.
Ryan will announce his starting line-up later today, but it is not expected to include Barkley.
Barkley could conceivably have gone straight into the side instead of centre Anthony Allen, who was carried off nursing an ankle injury during the 20-8 Leicester loss.
But former Wales back Matthew Watkins is tipped for a midfield starting spot alongside skipper Mike Tindall as Gloucester target an immediate riposte on a ground where they have never beaten Bath in the Premiership.
Reflecting on the Leicester setback, Ryan said: ''I am frustrated, but at the same time we know why we lost.
''We lost because we did things we hadn't talked about all week, and therefore we cannot hide from that.
''What we talked about all week would have been enough to beat Leicester.
''The small things that happened around the edge, and how we get distracted, is key. That's what is killing us in big games.''
Bath, conquerors of Bristol last Sunday, again look set to be without captain Michael Lipman while he continues his recovery from a head injury.
Bristol travel to Twickenham tomorrow, where opponents Harlequins' satisfaction at an opening weekend win has been tempered by fly-half Nick Evans' knee injury that could mean the New Zealander facing a month sidelined.
Elsewhere tomorrow, Leicester host London Irish, while tonight's Premiership action takes Saracens to Stockport and an appointment with a Sale Sharks side
bolstered by the return of fit-again England prop Andrew Sheridan.
Saracens boss Eddie Jones has made five changes from the team beaten narrowly by Quins last weekend, which include first starts this term for full-back Richard Haughton and hooker Fabio Ongaro.
On Sunday, Jonny Wilkinson will begin his comeback from shoulder surgery in Newcastle's Premiership clash against Kingston Park visitors Northampton.
Wilkinson underwent an operation earlier this summer and missed England's two-Test New Zealand tour.
Newcastle rugby director Steve Bates said: ''Jonny is in great shape and raring to go.
''I thought Rory Clegg did very well for an 18-year-old guy making his Premiership debut last weekend against Sale, but with a world-class talent like Jonny in the side, we will be a much more potent attacking force.
''The attention that the opposition have to give him often presents opportunities elsewhere on the field for other players.
''He knows what we as coaches are trying to achieve, and what he also brings is a great emphasis on precision in attack.
''He brings a huge amount of problems for defenders to deal with, firstly because he is a prolific goal kicker and teams are wary of conceding penalties in their own half, which in turn could well have implications on other areas of the game.''