Middlesex 7s at Twickenham on Saturday 12th August.
Strettle is joined in the 12-man squad by fellow new signing Will Skinner, while the team will be captained by Samoan scrum half Steve So'oialo. England Under 21 internationals Chris Robshaw and Tosh Masson will both feature and there is also a place for 19 year-old Josh Moore, who is currently on trial with the Quins Academy.
Quins opening match in the new-look tournament will be against last year's winners Gloucester at 11.18am, followed by Sale Sharks, the other team in pool two.
The full squad is as follows:
1. Will Skinner
2. Phil Burgess
3. Tom Guest
4. George Robson
5. Chris Robshaw
6. Tosh Masson
7. Seb Jewell
8. Josh Moore
9. Adam Thompstone
10. Tom Williams
11. David Strettle
12. Steve So'oialo (Capt.)