DetroitLions
- 3rd in NFC North
Detroit Lions Schedule 2021
| Regular Season | |||||||||
| WK | DATE | OPPONENT | RESULT | W-L | Hi Pass | Hi Rush | Hi Rec | ||
| 1 | Mon, 13 Sep | L41-33 | 0-1 | Goff 338 | Williams 54 | Hockenson 97 | |||
| 2 | Tue, 21 Sep | L35-17 | 0-2 | Goff 246 | Goff 46 | Hockenson 66 | |||
| 3 | Mon, 27 Sep | L19-17 | 0-3 | Goff 217 | Swift 47 | Raymond 68 | |||
| 4 | Mon, 4 Oct | L24-14 | 0-4 | Goff 299 | Williams 66 | Cephus 83 | |||
| 5 | Mon, 11 Oct | L19-17 | 0-5 | Goff 203 | Williams 57 | St. Brown 65 | |||
| 6 | Mon, 18 Oct | L34-11 | 0-6 | Goff 202 | Swift 24 | Hockenson 74 | |||
| 7 | Mon, 25 Oct | L28-19 | 0-7 | Goff 268 | Williams 57 | Raymond 115 | |||
| 8 | Mon, 1 Nov | L44-6 | 0-8 | Goff 222 | Swift 27 | Hockenson 89 | |||
| 9 | BYE WEEK | ||||||||
| 10 | Mon, 15 Nov | T16-16 OT | 0-8-1 | Goff 114 | Swift 130 | St. Brown 61 | |||
| 11 | Mon, 22 Nov | L13-10 | 0-9-1 | Boyle 77 | Swift 136 | Hockenson 51 | |||
| 12 | Fri, 26 Nov | L16-14 | 0-10-1 | Goff 171 | Williams 65 | Reynolds 70 | |||
| 13 | Mon, 6 Dec | W29-27 | 1-10-1 | Goff 296 | Williams 71 | St. Brown 86 | |||
| 14 | Mon, 13 Dec | L38-10 | 1-11-1 | Goff 215 | Reynolds 83 | St. Brown 73 | |||
| 15 | Mon, 20 Dec | W30-12 | 2-11-1 | Goff 216 | Reynolds 112 | St. Brown 90 | |||
| 16 | Mon, 27 Dec | L20-16 | 2-12-1 | Boyle 187 | Williams 77 | St. Brown 91 | |||
| 17 | Mon, 3 Jan | L51-29 | 2-13-1 | Boyle 262 | Swift 32 | St. Brown 111 | |||
| 18 | Mon, 10 Jan | W37-30 | 3-13-1 | Goff 238 | Williams 43 | St. Brown 109 | |||
| Preseason | |||||||||
| WK | DATE | OPPONENT | RESULT | W-L | Hi Pass | Hi Rush | Hi Rec | ||
| 1 | Sat, 14 Aug | L16-15 | 0-1 | Blough 76 | Reynolds 49 | Kennedy 46 | |||
| 2 | Sun, 22 Aug | L26-20 | 0-2 | Blough 143 | Reynolds 29 | Kennedy 61 | |||
| 3 | Sat, 28 Aug | L27-17 | 0-3 | Blough 117 | Jefferson 43 | Mills 46 | |||