Western IllinoisLeathernecks
- 1st in OVC-Big South
Western Illinois Leathernecks Schedule 2022
| Regular Season | |||||||
| DATE | OPPONENT | RESULT | W-L (CONF) | HI PASS | HI RUSH | HI REC | |
| Fri, 2 Sep | L42-25 | 0-1 (0-0) | Davenport 180 | Davenport 62 | Brantley 171 | ||
| Sun, 11 Sep | L62-10 | 0-2 (0-0) | Davenport 125 | Ogala 17 | Armstrong 72 | ||
| Sun, 18 Sep | L17-10 | 0-3 (0-0) | Bruno 220 | Bruno 84 | Brantley 116 | ||
| Sun, 25 Sep | L52-17 | 0-4 (0-1) | Bruno 166 | Reed 36 | Reed 52 | ||
| Sun, 2 Oct | L34-10 | 0-5 (0-2) | Bruno 129 | Reed 22 | Brantley 107 | ||
| Sun, 16 Oct | L30-7 | 0-6 (0-3) | Bruno 81 | Bruno 15 | Brantley 71 | ||
| Sun, 23 Oct | L28-27 | 0-7 (0-4) | Bruno 160 | Collins 61 | Brantley 66 | ||
| Sun, 30 Oct | L64-14 | 0-8 (0-5) | Bruno 207 | Dobbins 11 | Brantley 120 | ||
| Sun, 6 Nov | L56-17 | 0-9 (0-6) | Bruno 188 | Bruno 42 | Armstrong 85 | ||
| Sun, 13 Nov | L21-0 | 0-10 (0-7) | Bruno 193 | Collins 9 | Brantley 83 | ||
| Sun, 20 Nov | L20-13 OT | 0-11 (0-8) | Ogala 30 | Collins 163 | Armstrong 23 | ||