Mississippi Valley StateDelta Devils
- 1st in SWAC - East
Mississippi Valley State Delta Devils Schedule 2021
| Regular Season | |||||||
| DATE | OPPONENT | RESULT | W-L (CONF) | HI PASS | HI RUSH | HI REC | |
| Fri, 3 Sep | L35-0 | 0-1 (0-0) | Regan 56 | Johnson 38 | Williams 22 | ||
| Sun, 19 Sep | L58-13 | 0-2 (0-0) | Regan 99 | Johnson 89 | Myers 40 | ||
| Mon, 27 Sep | L38-25 | 0-3 (0-1) | Eason 210 | Johnson 87 | Clayton 109 | ||
| Sun, 3 Oct | W17-16 | 1-3 (0-1) | Eason 175 | Johnson 71 | Rankin 80 | ||
| Sun, 10 Oct | W20-14 | 2-3 (1-1) | Eason 137 | Johnson 96 | Porter 41 | ||
| Sun, 17 Oct | L24-12 | 2-4 (1-2) | Eason 70 | Johnson 123 | Porter 29 | ||
| Sun, 24 Oct | L31-28 | 2-5 (1-3) | Eason 215 | Williams 63 | Rankin 147 | ||
| Sun, 31 Oct | L28-19 | 2-6 (1-4) | Eason 125 | Johnson 119 | Rankin 36 | ||
| Sun, 7 Nov | L42-14 | 2-7 (1-5) | Regan 111 | Johnson 84 | Rankin 82 | ||
| Sun, 14 Nov | W44-31 | 3-7 (2-5) | Eason 315 | Thomas 88 | Rankin 152 | ||
| Sun, 28 Nov | W24-19 | 4-7 (3-5) | Eason 182 | Johnson 193 | Rankin 79 | ||