Michigan StateSpartans
- 1st in Big Ten
Michigan State Spartans Schedule 2021
| Regular Season | |||||||
| DATE | OPPONENT | RESULT | W-L (CONF) | HI PASS | HI RUSH | HI REC | |
| Sat, 4 Sep | W38-21 | 1-0 (1-0) | Thorne 185 | Walker III 264 | Reed 64 | ||
| Sun, 12 Sep | W42-14 | 2-0 (1-0) | Thorne 280 | Simmons 121 | Reed 181 | ||
| Sun, 19 Sep | W38-17 | 3-0 (1-0) | Thorne 261 | Walker III 172 | Nailor 82 | ||
| Sun, 26 Sep | W23-20 OT | 4-0 (2-0) | Thorne 183 | Walker III 61 | Mosley 70 | ||
| Sun, 3 Oct | W48-31 | 5-0 (2-0) | Thorne 327 | Walker III 126 | Nailor 128 | ||
| Sun, 10 Oct | W31-13 | 6-0 (3-0) | Thorne 339 | Walker III 233 | Nailor 221 | ||
| Sun, 17 Oct | W20-15 | 7-0 (4-0) | Thorne 126 | Walker III 84 | Reed 70 | ||
| Sun, 31 Oct | W37-33 | 8-0 (5-0) | Thorne 196 | Walker III 197 | Reed 80 | ||
| Sun, 7 Nov | L40-29 | 8-1 (5-1) | Thorne 276 | Walker III 136 | Reed 73 | ||
| Sun, 14 Nov | W40-21 | 9-1 (6-1) | Thorne 287 | Walker III 143 | Reed 114 | ||
| Sun, 21 Nov | L56-7 | 9-2 (6-2) | Thorne 158 | Collins 29 | Mosley 46 | ||
| Sun, 28 Nov | W30-27 | 10-2 (7-2) | Thorne 268 | Walker III 138 | Reed 89 | ||
| DATE | OPPONENT | RESULT | W-L (CONF) | HI PASS | HI RUSH | HI REC | |
| Chick-fil-A Peach Bowl | |||||||
| Fri, 31 Dec | W31-21 | 11-2 (7-2) | Thorne 354 | Simmons 23 | Nailor 108 | ||